With the Heretics freed from the 1903 prison world and taking over control of the town as revenge on the death of one of their own, Stefan and Lily come to a sort of uneasy truce. The towns people are evacuated and those that remain are fair game for the Heretics. Buildings lay in ruins and the few that have remained remain on constant guard. They need to choose, band together in attempts to reclaim their town, to rebuild it and try to make it how it once was or to leave and find a new life somewhere else. Damon refuses to leave Elena who remains spelled asleep while Bonnie continues to live. Stefan and Caroline, tired of living on the outskirts and trying to deal with the new threat, have fled to New Orleans to seek help from the Originals while Matt has taken it upon himself to try and help any humans that remain in Mystic Falls.
While the threat of Esther and Dhalia has passed there is no rest for the residents of New Orleans. As a final means of torturing her sons Esther resurrected Tatia having spelled her into a deep sleep for centuries, keeping her hidden from them. The power of the spell seeped into her the longer she remained under it, changing her in ways that no one thought possible. With several former Mystic Falls residents begin to come to the city, seeking out the help along with the fall out of Klaus' decision to have the Crescent wolves, including Hayley, cursed into wolf form save for during the full moon, the Originals the family is once again torn. Elijah wishes to help, finding it difficult to be around the woman he'd loved and killed centuries before not to mention dealing with the poachers who are stalking the Bayou killing the wolves to clear the land, meanwhile Klaus has other things concerning him. The arrival of Lucian, a vampire with a long history with the Originals, particularly Klaus, has the city fearing it's own safety. With the news of a new threat, however, he must take into consideration the safety of those he cares about and how best to deal with the situation.